Table 1.

Clinical and Demographic Characteristics

Subject Group	Age at Initial Scan Date	Age at First Treatmenta	Duration of Illnessb		PANSSc		MMSEd
				Positive	Negative	General
FULL BASELINE SAMPLE (n=145)
Healthy Subjects (n=41)	44.15±14.66						29.86±9.12
Schizophrenia Patients (n=104)	42.77±12.12	24.96±9.12	18.49±12.71	18.86±6.64	18.91±7.77	37.07±9.87	26.86±2.71
Good-Outcome Patients (n=51)	40.62±12.60	26.82±7.06	14.82±12.10	16.04±4.94	16.25±5.53	32.38±7.83	27.00±2.64
Poor-Outcome Patients (n=53)	44.79±11.39	22.82±10.74	22.74±12.20	21.74±6.94	21.60±8.72	41.81±9.42	26.72±2.80
FOLLOW-UP COHORT (n=65)
Healthy Subjects (n=16)	41.62±12.23						30.00±0.00
Schizophrenia Patients (n=49)	42.69±12.29	23.80±8.01	18.67±12.05	19.04±6.80	19.00±7.25	40.53±13.23	26.47±3.15
Good-Outcome Patients (n=23)	37.44±10.68	26.81±5.51	12.29±8.78	15.39±4.92	15.35±5.08	35.32±14.63	27.32±2.36
Poor-Outcome Patients (n=26)	47.35±11.90	20.96±9.05	24.77±11.71	22.4±6.64	22.36±7.40	45.12±10.05	25.79±3.56
DROP-OUT SAMPLE (n=80)
Healthy Subjects (n=25)	45.62±15.75						29.77±0.53
Schizophrenia Patients (n=55)	43.19±12.37	25.38±9.88	18.40±13.08	18.38±6.20	19.00±8.46	35.52±10.14	27.20±2.43
Good-Outcome Patients (n=28)	42.21±13.25	26.46±8.10	16.54±13.66	16.96±5.53	16.52±5.98	33.27±7.83	27.36±2.08
Poor-Outcome Patients (n=27)	43.62±11.53	23.90±11.98	20.95±12.12	20.36±6.63	21.23±9.87	40.04±8.86	27.35±2.41

^aDocumented age at the time of first exposure to antipsychotic agents.

^bTime (in years) since the first illness-related exposure to antipsychotic agents to the initial scan.

^cPositive and Negative Syndrome Scale.

^dMini-Mental State Examination.