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Histopathologic alterations of ovaries from women with family history of ovarian cancer
| Present | Absent | |
| Histologic | ||
| Metaplasia of surface epithelium | [13] | [14-17] |
| Papillomatosis | ||
| Stratification | ||
| Epithelial inclusion cysts | ||
| Invaginations | ||
| Stromal hyperplasia | [13] | [14,15] |
| Cytologic | ||
| Nuclei of the surface epithelium | [14,16,18] | |
| Larger nuclei | ||
| Irregular contours | ||
| Heterogenous dense chromatin | ||
| Molecular | ||
| Increased expression of p53, c-erbB and Ki-67 | [15,19] |
