TABLE 1.

Hemodynamic parameters in mesenteric microcirculation of WT, recessive yellow e/e, and MC3R-null mice

Treatment and genotype	Venule diameter (μm)	Cell flux (cells/min)	Wall shear rate (s−1)
Sham WT	26.3 ± 1.7	19.4 ± 3.7	402.5 ± 12.5
I/R WT	29.2 ± 0.8	17.5 ± 3.3	293.7 ± 29.5
Sham MC3R-null	27.7 ± 1.6	13.5 ± 2.3	376.1 ± 46.0
I/R MC3R-null	26.6 ± 3.8	11.1 ± 2.8	363.1 ± 38.2
Sham recessive yellow e/e	28.0 ± 1.3	16.7 ± 1.0	415 ± 18.6
I/R recessive yellow e/e	25.8 ± 2.0	14.4 ± 2.8	314.7 ± 19.5

Diameters of the mesenteric vessels analyzed in Figs. 1 and 5 are reported. Similarly, values for wall shear rate and cell flux are shown. In all cases, mice were exposed to I/R (35 min of ischemia and 90 min of reperfusion) per the procedure described in Materials and Methods. Data are means ± se; 6 mice/group.