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I/R of mesenteric microcirculation and systemic leukocyte differential counts in WT and MC3R-null mice
| Treatment and genotype | PMN (106/ml) | PBMC (106/ml) |
|---|---|---|
| Sham WT | 4.8 ± 0.9 | 32.6 ± 4.6 |
| I/R WT | 16 ± 1.2 | 38.5 ± 6.3 |
| Sham MC3R-null | 7.2 ± 2.1 | 36.6 ± 5.5 |
| I/R MC3R-null | 20 ± 2.2 | 41.6 ± 7.5 |
Peripheral blood was analyzed by light microscopy in sham-treated animals or in mice subjected to 35 min ischemia and 90 min reperfusion of the superior mesenteric artery. Data are means ± se; 6 mice/group.
