Table 2.
Patient profiles with missing or incomplete rules, and corresponding rules extracted from the database *
| Patient subgroups | Learnt rules | ||||
|---|---|---|---|---|---|
| Profile # | Number of patients | For type of treatment (instances; confidence rate) [rule precision] | For pharmaco- therapeutic class (instances; confidence rate) [rule precision] | For INN (instances; confidence rate) [rule precision] | For Dose (instances; confidence rate) [rule precision] |
| 3 | 7 | Diet and exercise (7;1) [100%] | Not applicable | ||
| 4 | 51 | Monotherapy (45;1) [100%] | sulfonylurea if dyslipidemia (7;0.89), else alpha glucosidase inhibitors if not already under biguanides (3;0.8); biguanides by default (11;0.92) [100%] | ||
| 5 | 59 | Bitherapy (56;1) [100%] | Biguanides and sulfonylurea [100%] | Metformine and gibenclamide [100%] | |
| 6 | 16 | Insulin [+OAD]** if cholesterolemia ≤ 400 mg/dl (2;0.75), Tritherapy if not (12;0.93) [100%] | Biguanides, sulfonylurea and alpha glucosidase inhibitors if tritherapy [100%] | ||
| 7 | 84 | Insulin [+OAD]** (75;1) [100%] | Insulin only if already under insulin plus biguanides (62;0.65); Insulin with biguanides if postprandial glycemia >184 mg/dl and age<52 yrs (11;0.92); Insulin with sulfonylurea and alpha glucosidase inhibitors if already under sulfonylurea (11;0.63) [100%] | ||
| 12 | 1 | Oral bitherapy (mentioned in the guideline) | Biguanides and sulfonylurea [100%] | ||
| 13 | 39 | Oral bitherapy (mentioned in the guideline) | Biguanides and sulfonylurea if bitherapy [100%] | ||
| 14 | 18 | Insulin [+OAD]** (mentioned in the guideline) | |||
| 15 | 18 | Insulin [+OAD]** if morning glycemia >230 mg/dl (8;0.8), tritherapy if not (10;0.92) [100%] | Biguanides, sulfonylurea and alpha glucosidase inhibitors if tritherapy [100%] | ||
| 16 | 123 | Insulin [+OAD]** (114;1) [100%] | Insulin only if already under insulin plus sulfonylurea or insulin only (72;0.78); Insulin plus biguanides if already under insulin plus biguanides (24.5;0.83); insulin plus biguanides and sulfonylurea if not (17;0.36) [90.9%] | One injection of Insulin if accompanied by biguanides or sulfonylurea (10;0.83); Two injections of insulin [+OAD]** (104;0.79) [72.7%] | |
* Rules are separated according to the typology of treatment: the level of detail increases from left to right. Following each rule, its number of instances and confidence rate are presented in parentheses and the rule precision is given in square brackets.
** Insulin [+OAD]: Insulin alone or with oral anti-diabetic drugs.