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Schematic organization of domains of bifunctional TspGWI enzyme. (A) TspGWI subunits organization. Black block – catalytic domain, diagonal lines – MTase domain, grey block – MTase helical domain; white block – variable region, putative DNA specificity subunit. (B) Typical HsdM subunit organization. (C) Typical HsdR subunit organization. (D) Typical HsdS subunit organization.
