Table 1.

The pattern of motifs in the core promoter has a significant association with gene expression in a group of holdout genes not used in motif discovery analysis.

		Module
Correlation (microarray):		Contractile		Energy Generation		Protein Translation
		High	Low	High	Low	High	Low
Pattern:	Yes:	74	1638	152	1371	35	178
	No:	13	768	25	437	51	1429
Odds Ratio:		2.66 (1.46 – 5.28)		1.93 (1.24 – 3.13)		5.50 (3.37 – 8.89)
Fisher's p <		5.65e-4		2.03e-3		1.16e-11

Contingency tables show the relationship between the pattern of motifs in the core promoter region and the expression patterns of genes in the test group (n = 3473), not used during motif the discovery procedure. The correlation thresholds were set to r > 0.8 (high) and r < 0 (low). The odds ratio measures the strength of association between the pattern of motifs in each promoter and the pattern of expression. The 95% confidence interval of the odds ratio is shown in parentheses. The p-value calculated using Fisher's exact test is given in the bottom row.