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(A) AQP-2 expression in control kidneys and HA (3.75%, 235 kDa) cultured kidneys with and without HA-ase. (B) AQP-2 expression in kidneys cultured with various MW HA solutions (ANOVA, P ≤0.00001). * = P ≤ 0.05, ** = P ≤ 0.005, *** = P ≤ 0.0005, **** = P ≤ 0.00005
