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Classification of randomized trials of colorectal cancer follow-up
| Trials [Reference] | Follow-up programs compared | CEA testing used | Liver Imaging testing used |
| Makela [36] | Intense vs. Conventional | Yes | Yes |
| Ohlsson [37] | Intense vs. Minimal | Yes | No |
| Kjeldsen [38] | Intense vs. Minimal | No | No |
| Schoemaker [39] | Intense vs. Minimal | No* | Yes |
| Pietra [40] | Intense vs. Conventional | Yes | Yes |
| Secco [41] | Intense vs. Minimal | Yes | Yes |
* Isolated increase in CEA levels did not trigger further investigations.
