Table 4.
Results of randomized trials of follow-up after resection of colorectal cancer.
| Study, Year [Reference] | Follow-up Program intensity | Number of Patients Randomized | Median Observation (months) | Overall Recurrence Rate (%) | Number of Second Bowel Cancers | Radical Reoperation Rate (%) | 5-year Survival Rate (%) |
| Makela 1995 [36] |
Less More |
54 52 |
>60 | 39 42 |
NR | 14 23 |
54 59 |
| Ohlsson 1995 [37] |
Less More |
54 53 |
82 | 33 32 |
NR | 17 29 |
67 75 |
| Kjeldsen 1997 [38] |
Less More |
307 290 |
>60 | 26 26 |
3 7 |
NR | 68 70 |
| Schoemaker 1998 [39] |
Less More |
158 167 |
>60 | NR | 5 3 |
NR | 70 76 |
| Pietra 1998 [40] |
Less More |
103 104 |
>60 | 19 25a |
1 0 |
10 65 |
58 73b |
| Secco 2002 [41] |
Less More |
145 192 |
>60 | 53 57 |
NR | 16 31 |
48 63 |
Note: NR, not reported. a p < 0.01 b p < 0.05