Table 4.
Mean full-thickness cell densities (unweighted for distance between frames) estimated by manual and automatic methods at each examination before and after LASIK
| Mean Cell Density, cells/mm3 Mean ± SD |
||||||||
|---|---|---|---|---|---|---|---|---|
| Pre-LASIK | 1 month | 3 months | 6 months | 1 year | 2 years | 3 years | 5 years | |
| Number of patients | 17 | 17 | 17 | 17 | 17 | 15 | 17 | 16 |
| Manual | 32765 ± 3944 | 28114 ± 4193 | 28338 ± 4246 | 28903 ± 2,326 | 27492 ± 3568 | 26038 ± 2881 | 26195 ± 1739 | 22920 ± 1728 |
| Automatic | 31422 ± 3564 | 27696 ± 2399 | 28130 ± 3258 | 27368 ± 2161 | 25500 ± 2333 | 26460 ± 1755 | 25139 ± 2554 | 24311 ± 2276 |
| Difference | -1343 ± 3047 | -418 ± 3898 | -208 ± 2997 | -1535 ± 2525 | -1993 ± 3575 | 422 ± 2228 | -1056 ± 1503 | 1392 ± 1780 |
| Difference as percent of manual | -4.1 | -1.5 | -0.7 | -5.3 | -7.2 | 1.6 | -4.0 | 6.1 |
| P:* | 0.06 | 0.19 | 0.80 | 0.02 | 0.007 | 0.44 | 0.02 | <0.001 |
| MDD:a | 1857 | 1776 | 2030 | - | - | 1534 | - | - |
*
Probability, generalized estimating equation models
a
MDD : minimum detectable difference, cells mm-3, based on generalized estimating equation models, α = 0.05, β = 0.20.