Table 5.

Significance of difference between cell density after LASIK and density before LASIK

	Significance of difference in cell density from pre-LASIK
	1 month	3 months	6 months	1 year	2 years	3 years	5 years
Manual Assessment
Anterior flap	0.0009	0.0008	0.0006	<0.0001	<0.0001	<0.0001	<0.0001
Posterior flap	<0.0001	0.0005	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001
Anterior RAZ	0.0029	0.0015	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001
Posterior RAZ	0.0037	ns	ns	ns	ns	0.0044	<0.0001
66-90%	0.0054	ns	ns	0.0059	ns	0.0057	<0.0001
90-100%	ns	ns	ns	ns	0.0002	ns	0.0004
Automatic Assessment
Anterior flap	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001
Posterior flap	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001
Anterior RAZ	ns	ns	ns	0.0001	0.0021	0.0003	<0.0001
Posterior RAZ	ns	ns	ns	ns	ns	ns	ns
66-90%	ns	ns	ns	0.0059	ns	ns	<0.0001
90-100%	ns	ns	ns	ns	ns	ns	ns

ns = not significantly different (Generalized estimating equation models, Bonferroni correction for seven comparisons, P>0.05/7).