Table 1.
Baseline Characteristics of Study Subjects for the Incidence Radiographic hip OA (RHOA) and the Progression RHOA study.
Incidence Study |
Progression Study |
|||
---|---|---|---|---|
No RHOA (n=169)* |
Incident RHOA (n=167)* |
Stable RHOA (n=173)* |
Progression of RHOA (n=168)* |
|
Age (years) (Mean ± SD) |
69.6 ± 3.7 | 70.8 ± 4.6 † | 71.8 ± 5.5 | 72.2 ± 5.5 |
Weight (kg) (Mean ± SD) |
67.5 ± 11.2 | 67.4 ± 12.3 | 67.2 ± 11.4 | 68.3 ± 12.5 |
Height (cm) (Mean ± SD) |
159.4 ± 5.6 | 159.9 ± 6.1 | 157.7 ± 6.1 | 160.0 ± 6.6 ‡ |
Hip pain (% Positive) |
58 (35%) | 57 (35%) | 64 (37%) | 79 (47%) |
Estrogen use (% Positive) |
24 (14%) | 24 (14%) | 16 (9%) | 26 (16%) |
Vitamin D use (% Positive) |
83 (51%) | 75 (46%) | 87 (51%) | 82 (50%) |
Femoral Neck BMD (g/cm2) (Mean ± SD) |
0.66 ± 0.10 | 0.67 ± 0.11 | 0.65 ± 0.11 | 0.70 ± 0.13 |
Baseline serum COMP (u/L) (Mean ± SD) |
11.06 ± 3.32 | 10.55 ± 2.93 | 10.66 ± 3.21 | 11.17 ± 3.60 |
Visit 4 Serum COMP (u/L) (Mean ± SD) |
10.78 ± 2.98 | 12.27 ± 3.73 | 11.60 ± 3.54 | 11.08 ± 3.58 |
Baseline serum NTX (nM BCE) (Mean ± SD) |
20.29 ± 8.97 | 20.52 ± 7.98 | 20.68 ± 7.29 | 20.89 ± 7.24 |
Visit 4 Serum COMP (nM BCE) (Mean ± SD) |
19.54 ± 5.66 | 20.95 ± 7.86 | 20.43 ± 7.62 | 20.34 ± 6.47 |
Number of subjects ( ) represents all subjects with baseline characteristics and covariates collected.
RHOA=radiographic hip osteoarthritis, BMD=bone mineral density
p<0.05 versus subjects without RHOA
p<0.005 versus subjects with stable RHOA