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. 2009 Apr 20;185(2):291–303. doi: 10.1083/jcb.200811105

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© 2009 Manzl et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 8. — Subcellular localization of caspase-2 in the absence of PIDD or RAIDD. Localization of endogenous caspase-2 (green) was detected in wild-type SV40-immortalized MEFs and MEFs lacking pidd or raidd before (control) or after drug treatment (50 µg/ml etoposide). Cells were costained for p53 (red) and the nucleus detecting fluorochrome DAPI (blue). Overlays of all staining are depicted (merge).