Table 2.
Case No. | Sex | Age | Site | Size (cm) | Mitoses (/50 HPF) | Differentiation | CD117 | Diagnosis | KIT mutations | PDGFRA mutations |
1 | F | 72 | LI | 9 | 6 | SP | N | Malignant potential | wt | wt |
2 | M | 65 | SI | 2.8 | 10 | M1 | P | Malignant potential | p.A502-Y503insA | wt |
3 | M | 79 | S | 16 | 9 | EP | P | Malignant potential | p.K558>NP | wt |
4 | F | 60 | SI | 17 | 3 | EP | P | Malignant potential | p.K558>NP | wt |
5 | F | 59 | SI | 5 | 2 | SP | P | Low malignant potential | p.W557-K558del | wt |
6 | M | 72 | SI | 7.8 | 2 | SP | P | Malignant potential | p.W557-K558del | wt |
7 | M | 82 | S | 5.5 | 5 | SP | P | Very low malignant potential | p.D579del | wt |
8 | M | 52 | SI | 4 | 3 | SP | P | Low malignant potential | p.V559A | wt |
9 | F | 63 | S | 8 | 7 | SP | P | Malignant potential | p.V559A | wt |
10 | F | 70 | SI | 6 | 1 | M1 | P | Malignant potential | p.W557-K558del | wt |
11 | F | 60 | S | 9 | 4 | M1 | P | Very low malignant potential | wt | p.D842V |
12 | M | 61 | S | 13 | 2 | M2 | P | Low-moderate malignant potential | wt | p.I 843-D846del |
13 | M | 64 | S | 9 | 3 | SP | P | Very low malignant potential | wt | wt |
14 | F | 70 | S | 1.5 | 1 | SP | P | Benign | p.P551-Q556del | wt |
15 | M | 66 | S | 10 | 20 | SP | P | Malignant potential | wt | wt |
16 | M | 60 | SI | 12 | 4 | SP | P | Malignant potential | p.Y503-F504insAY | wt |
17 | F | 62 | SI | 3.5 | 1 | SP | P | Low malignant potential | pV560D | wt |
18 | M | 56 | SI | 4 | 1 | SP | P | Low malignant potential | p.K550-E554del | wt |
19 | F | 67 | S | 19 | 22 | M1 | P | Malignant potential | p.K550-K558del | wt |
20 | F | 46 | S | 19 | 10 | EP | P | Malignant potential | wt | wt |
21 | F | 61 | S | 3.5 | 3 | SP | P | Very low malignant potential | wt | wt |
22 | M | 57 | LI | 8 | 5 | SP | P | Malignant potential | pV560D | wt |
23 | M | 58 | S | 0.7 | 0 | SP | P | Benign | p.V559-G565del | wt |
24 | M | 60 | S | 7.5 | 3 | M2 | P | Very low malignant potential | wt | wt |
25 | M | 67 | S | 8 | 1 | M2 | P | Very low malignant potential | wt | wt |
26 | M | 72 | S | 5.5 | 1 | SP | P | Very low malignant potential | p.Y503-F504insAY | wt |
27 | F | 70 | LI | 17 | 9 | SP | P | Malignant potential | p.W557-K558del | wt |
28 | M | 61 | LI | 2.6 | 6 | SP | P | Malignant potential | p.P551-K558del | wt |
29 | F | 53 | S | 5 | 0 | SP | N | Very low malignant potential | wt | wt |
30 | F | 57 | LI | 2.5 | 0 | SP | P | Low malignant potential | wt | wt |
S: Stomach; SI: Small intestine; LI: Large intestine; SP: Spindle cell; EP: Epithelioid; M1: Mixed type 1; M2: Mixed type 2; P: Positive; N: Negative.