Table 1.
Clinical and biochemical profiles of patients on propranolol or propranolol and spironolactone
| Characteristics | Group A n = 17 | Group B n = 18 | P value |
| Male:Female ratio | 12:5 | 15:3 | |
| Age (yr) | 44.3 ± 7.98 | 46.61 ± 8.71 | 0.09 |
| Ascites | 10 | 8 | |
| Encephalopathy | 1 | 2 | |
| Etiology | |||
| Alcoholic | 6 | 10 | |
| Hepatitis-B | 6 | 2 | |
| Hepatitis-C | 0 | 1 | |
| Others | 5 | 5 | |
| Varices | |||
| II | 3 | 4 | |
| III | 11 | 9 | |
| IV | 3 | 5 | |
| Child’s score | |||
| A | 3 | 4 | |
| B | 8 | 9 | |
| C | 6 | 5 | |
| Bilirubin (mg/dL) | 2.26 ± 1.8 | 2.13 ± 2.13 | 0.85 |
| Albumin (mg/dL) | 2.89 ± 0.46 | 2.71 ± 0.78 | 0.42 |
| Globulin (mg/dL) | 3.72 ± 0.76 | 4.64 ± 2.26 | 0.12 |
| ALT (IU/L) | 79.35 ± 75.43 | 43.89 ± 18.20 | 0.08 |
| Urea (mg/dL) | 29.53 ± 11.03 | 28.6 ± 13.57 | 0.83 |
| Creatinine (mg/dL) | 0.88 ± 0.27 | 0.84 ± 0.28 | 0.67 |
| Na+ (mEq/L) | 135.7 ± 4.9 | 133.22 ± 4.61 | 0.13 |
| K+ (mEq/L) | 3.74 ± 0.56 | 3.66 ± 0.49 | 0.64 |
| Prothrombin time (INR) | 1.21 ± 0.16 | 1.34 ± 0.40 | 0.30 |
| Dose of propranolol (mg/d) | 92.94 ± 23.39 | 88.89 ± 20.83 | 0.59 |
Values are shown as mean ± SE, P < 0.05 considered statistically significant. Group A: Propranolol; Group B: Propranolol and Spironolactone; ALT: Alanine aminotransferase.