Table 2.
Hemodynamic parameters at baseline and on d 8 of therapy
| Characteristics |
Group A (n =17) |
Group B (n =18) |
Group A vs Group B P-value |
|||||
| Baseline | d 8 | P-value | Baseline | d 8 | P-value | Baseline | d 8 | |
| Pulse rate (/min) | 86.80 ± 12.0 | 69.17 ± 8.66 | 0.058 | 79.89 ± 10.21 | 64.66 ± 8 | 0.00003 | 0.08 | 0.12 |
| SBP (mmHg) | 123.88 ± 11.82 | 117.41 ± 9.45 | 0.0003 | 123.76 ± 11.3 | 118.44 ± 8.85 | 0.001 | 0.98 | 0.74 |
| IVCP (mmHg) | 7.29 ± 3.33 | 7.19 ± 2.95 | 0.89 | 7.33 ± 3.6 | 7.11 ± 3.34 | 0.74 | 0.97 | 0.95 |
| FHVP (mmHg) | 7.88 ± 3.12 | 8.82 ± 3.99 | 0.28 | 8.22 ± 3.64 | 9.00 ± 3.14 | 0.25 | 0.76 | 0.86 |
| WHVP (mmHg) | 24.65 ± 3.23 | 23.88 ± 5.11 | 0.54 | 24.56 ± 4.3 | 20.78 ± 3.83 | 0.00009 | 0.94 | 0.052 |
| HVPG (mmHg) | 16.76 ± 2.66 | 15.06 ± 4.35 | 0.04 | 16.11 ± 1.97 | 11.78 ± 2.07 | - | - | - |
| RAP (mmHg) | 4.88 ± 2.87 | 6.25 ± 2.57 | 0.007 | 5.11 ± 2.59 | 5.78 ± 2.39 | 0.27 | 0.81 | 0.58 |
| MPAP (mmHg) | 17.46 ± 3.91 | 19.58 ± 4.8 | 0.32 | 18.11 ± 4.43 | 18.80 ± 4.29 | 0.60 | 0.76 | 0.82 |
| PCWP (mmHg) | 14.54 ± 6.78 | 14.33 ± 6.82 | 0.94 | 15.50 ± 4.53 | 14.40 ± 4.95 | 0.48 | 0.69 | 0.98 |
All the values are shown as mean ± SE. P < 0.05 considered statistically significant. SBP: Systolic blood pressure; IVCP: Inferior vena cava pressure; FHVP: Free hepatic venous pressure; WHVP: Wedge hepatic venous pressure; HVPG: Hepatic venous pressure gradient; RAP: Right atrial pressure; MPAP: Mean pulmonary artery pressure; PCWP: Pulmonary capillary wedge pressure; Group A: Propranolol; Group B: Propranolol and Spironolactone.