Table 2.
Studies on sensitivity of interferon gamma assays in contacts of infectious TB patients
| Close contacts (high exposure) | Casual contacts (low exposure) | BCG (all) % | |||||
|---|---|---|---|---|---|---|---|
| No. | TST + (%) | IGRA + (%) | No. | TST + (%) | IGRA + (%) | ||
| Lalvani[37]* | 22 | 65 | 72 | 20 | 32 | 0 | 82 |
| Ewer[36]* | 101 | 58 | 62 | 386 | 20 | 17 | 87 |
| Brock[39]** | 45 | 53 | 55 | 40 | 10 | 5 | 0 |
| Kang[28]** | 48 | 71 | 44 | 72 | 60 | 10 | 81 |
| Shams[40]* | 104 | 57 | 50 | 103 | 41 | 30 | 49 |
| Zellweger[41]* | 54 | 50 | 22 | 37 | 35 | 13 | 86 |
| Hill[42]* | 163 | 32 | 28 | 182 | 8 | 10 | 46 |
| Nakaoka[38]** | 72 | 53 | 74 | 39 | 15 | 10 | 90 |
| Diel[43]** | 124 | 23 | 17 | 232 | 9 | 1 | 46 |
*
T SPOT - TB assay,
**
QuantiFERON®- TB Gold assay, TST - Tuberculin skin test, IGRA - Interferon gamma release assays, BCG - Bacille Calmette-Guérin