A Working Model of Activation of SOS2 by SCaBP8 in Shoots and by SOS3 in Roots.
(A) In shoot tissue, SCaBP8 recruits SOS2 to the plasma membrane and then the salt-induced phosphorylation strengthens the SCaBP8-SOS2 complex at the plasma membrane. SOS2 then phosphorylates and activates SOS1.
(B) In root tissue, the N-terminal myristoylation of SOS3 recruits SOS2 to the plasma membrane. SOS2 phosphorylates and activates SOS1.
SC8, SCaBP8; M, myristoylation; P, phosphorylation.