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. 2008 Jan-Jun;1(1):21–33. doi: 10.4103/0974-2700.40573

Table 8.

Preventive measures for leptospirosis

Animal surveys of a locale
 Animal surveys of an area help determine the reservoir of the leptospires and examine the size of the population of these host animals. In addition, culturing of kidney tissue from these host animals can help detect the leptospiral serovars in a particular area
Water and soil samples
 These studies are primarily retrospective and not hightly effective in controlling leptospirosis
Rodent control
 Installation of fences and screens to exclude rats and feral animals
 Rodent-proofing of buildings
 Removal of food and trash from recreational areas which may attract rodents and other feral animals
 Trapping and poisoning of rats and feral animals
 Warning signs for potentially contaminated areas
 Limiting access to potentially infected water sources and mud
Hygiene and sanitation
 Provision of safe drinking water
 Protective clothing (gloves, boots, glasses, aprons, and masks)
 Sanitary procedures (washing hands)
 Washing and (occlusive) bandaging of wounds
 Avoidance of potentially contaminated water and soil
 Avoidance of potentially contaminated body fluids and tissues
 Antibiotic prophylaxis
 Vaccines
 Litter control
Disinfection and cleaning
 Disinfection of contaminated areas (barns, slaughterhouses)
 Cleaning with antibacterial cleaning solution or a solution of 1 part household bleach in 10 parts water
 Bleach, acids, alkalis, chlorines, disinfectants, UV filtration, steam-cleaning, irradiation, and drying will typically kill leptospires
Harvesting
 Use machinery when possible for harvesting thus reducing human contact with potentially infected animals and environmental sources
Prevention of domestic livestock
 Buying certified leptospire-free animals
 Avoiding communal pastures if possible
  By keeping sheep and infected animals out of a pasture for at least 2 months will usually provide sufficient time for any leptospires present in the field to die because drying and sunlight will kill the leptospires
 Isolation and slaughtering of infected animals
 Antibiotics for potential leptospite sheeding
 Vaccines
  Serovars icterohemorrhagiae and canicola for dogs
  Serovars hardjo and pomona for cattle
  Serovars pomona, tarassovi and bratislava for pigs
 Proper disposal of animal waste to prevented infection in uninfected animals and humans
Effective laboratory safety procedures
Education
 Causative organism
 Signs and symptoms
 Control and prevention measures
 Treatment