Figure 1.

An alignment of TROVE modules. The alignment was generated using MAFFT [15]. The alignment has been coloured using Chroma with the default colouring scheme [16]. The 4^th position in the RNP-1 motif proposed by van Horn et al [12] in marked with an asterisk. The Swiss-Prot or GenBank accession numbers for the proteins in the alignment are as follows: Cthermocellum (ZP_00060193), Scoelicolor (Q9X9W7), Tthermophila_p80 (Q94818), Mmusculus_TEP1 (P97499), Hsapiens_TEP1 (Q99973), Npunctiforme (ZP_00108461), Dradiodurans_Ro (Q9RUW8), Celegans_Ro (Q27274), Mmusculus_Ro (O08848), Styphimurium (Q8ZLH8), Pfluorescens (ZP_00086137).