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. 2003 Oct 28;4:16. doi: 10.1186/1471-2121-4-16

Figure 3.

Figure 3

Overexpression of TLK1B-KD results in missegregation of chromosomes and other mitotic abnormalities. a. A normal metaphase in MM3MG-KD cells. b. Multi-polar spindles frequently found in MM3MG-TLK1B-KD cells. c. Unequal segregation of chromosomes in MM3MG-TLK1B-KD cells. d. Persistence of microtubules from the mitotic spindle after metaphase. e. Persistence of microtubules after cytokinesis found frequently in MM3MG-TLK1B-KD cells. f. A representative metaphase chromosome spread with 84 chromosomes from an MM3MG-TLK1B-KD cell.