Table 3.
HLA DRB1 and DQB1 alleles in indian RSA patients
| HLA | Patients (N = 28) | Controls (N = 88) | OR | χ2 | EF | PF | P-value | ||
|---|---|---|---|---|---|---|---|---|---|
| N+ | AF (%) | N+ | AF (%) | ||||||
| DRB1 | |||||||||
| *010101 | 1 | 1.78 | 15 | 8.52 | 0.2 | 0.019 | 0.04 | 0.071 | |
| *030101 | 10 | 17.85 | 6 | 3.40 | 7.6 | 0.15 | 0.14 | 0.0001* | |
| *040301 | 1 | 1.78 | 7 | 3.97 | 0.4 | 0.001 | 0.01 | ||
| *070101 | 8 | 14.28 | 23 | 13.06 | 1.1 | 0.002 | |||
| *080101 | 1 | 1.78 | 1 | 0.56 | 3.2 | 0.024 | 0.02 | ||
| *090102 | 1 | 1.78 | 7 | 3.97 | 0.4 | 0.001 | 0.01 | ||
| *100101 | 7 | 12.50 | 15 | 8.52 | 1.6 | 0.012 | 0.04 | 0.071 | |
| *110101 | 1 | 1.78 | 19 | 10.79 | 0.1 | 0.031 | 0.06 | 0.027 | |
| *1404 | 4 | 7.14 | 9 | 5.11 | 1.5 | 0.007 | |||
| *150101 | 18 | 32.14 | 24 | 13.63 | 4.8 | 0.122 | 0.25 | 0.0003* | |
| DQB1 | |||||||||
| *0201 | 8 | 14.28 | 9 | 5.11 | 3.5 | 0.062 | 0.10 | 0.016 | |
| *030101 | 1 | 1.78 | 2 | 1.13 | 1.6 | 0.01 | |||
| *0302 | 3 | 5.35 | 3 | 1.7 | 3.4 | 0.034 | 0.03 | ||
| *030302 | 7 | 12.50 | 12 | 6.81 | 2.1 | 0.025 | 0.06 | ||
| *050101 | 10 | 17.85 | 13 | 7.38 | 3.2 | 0.063 | 0.11 | 0.015 | |
| *060101 | 20 | 35.71 | 52 | 29.34 | 2.3 | 0.042 | 0.19 | 0.004* | |
N+ - Number positive; χ2 - Chi square with Yates correction; AF (%) - allele frequency percentage; OR - Odds ratio; EF - Etiological fraction; PF - Preventive fraction
*
Significant P-value