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Effect of MgATP, ATP alone, and CaATP on Cl− current of CFTR-D1370N. (A) Example of macroscopic current. Measurements were made in the presence of either 0 or 4 mM Mg2+ or Ca2+ and 1 mM ATP as indicated by bars. (B) Effect of divalent ion–ATP complexes on current: MgATP is shown as 100%; n = 4. *, P < 0.05 compared with MgATP.
