Figure 4.

Ketamine or saline were administered just before the “initial” exposure between two animals making up three different groups, those that were treated with water only, haloperidol (2mg/kg/day) or olanzapine (4mg/kg/day) for 30 days. At the “trial” exposure, social recognition was present in the water/saline condition but reduced by water/ketamine; while subchronic treatment with olanzapine but not haloperidol reduced the initial responding, both antipsychotic drugs (haloperidol/ketamine and olanzapine/ketamine) blocked the disruptive action of ketamine on social learning.