Table 4.
Genotype and minor allele frequencies in coronary artery disease cases (n = 1,299) and controls (n = 484) of the AtheroGene study (Mainz, Germany)
| Genotype frequency (%) | p value | Minor allele frequency | ||||
|---|---|---|---|---|---|---|
| 11 | 12 | 22 | ||||
| T-512C | Cases | 46.6% | 43.6% | 9.8% | 0.32 | |
| Controls | 46.0% | 43.4% | 10.6% | 0.88 | 0.32 | |
| T-123/in1C | Cases | 60.4% | 33.9% | 5.7% | 0.23 | |
| Controls | 57.7% | 36.9% | 5.4% | 0.50 | 0.24 | |
| R38C | Cases | 96.4% | 3.5% | 0.1% | 0.02 | |
| Controls | 95.4% | 4.6% | 0.0% | 0.50 | 0.02 | |
| C+264A | Cases | 90.0% | 9.8% | 0.2% | 0.05 | |
| Controls | 90.4% | 9.6% | 0.0% | 0.68 | 0.05 | |
| G+303C | Cases | 96.0% | 4.0% | 0.0% | 0.02 | |
| Controls | 94.8% | 5.2% | 0.0% | 0.29 | 0.03 | |
11 homozygotes for the major allele, 12 heterozygotes, 22 homozygotes for the minor allele