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. 2009 Jun 11;106(25):10332–10337. doi: 10.1073/pnas.0810793106

Fig. 3.

Fig. 3.

Telemetric analysis of physiological parameters in Tph2-deficient mice. (A) Changes in the body temperature and locomotor activity after a challenge by a cold (4 °C) environment. Filled circles, Tph2−/− (n = 7); open circles, control mice (n = 8) (4-month-old female mice, FVB/N F4 genetic background). Circadian variations in sleep (B), mean arterial blood pressure (BP) (C), heart rate (HR) in beats per minute (bpm) (D), and respiratory rate (RR) in breaths per minute (Bpm) (E) in Tph2-deficient 3-month-old female mice (FVB/N F4 genetic background). Bold line indicates nighttime. Filled circles, Tph2−/− (n = 5), open circles, control mice (n = 5). *, P < 0.05; **, P < 0.01; and ***, P < 0.001 (Student's t test) Tph2−/− vs. control mice at the same time point.