Figure 4. Chromosomal aberrations in dRecQ4¹⁴ mutant cells.

Mitotic chromosome patterns of wild type and dRecQ4¹⁴mutant larval brains are shown in (A), (B) and (C). (A) Normal pattern of metaphase chromosomes for wild type cells. (B) and (C) show typical metaphase chromosomes of dRecQ4¹⁴ mutant cells. In (B), sister chromatids are precociously separated, while in (C) chromosomes are mostly broken into smaller fragments. The percentage of cells for the three categories in wild type and dRecQ4¹⁴ mutants is shown below. Total cell numbers analyzed in each case are indicated in parenthesis. Scale bar = 5 µm