Table 3. A comparison of the European and American CLSI threshold values for cefotaxime.

	Antibacterial substance	Organism-specific threshold value assignments
		Entero-bacteriaceae	Pseudomonas	Acinetobacter	Staphylococcus	Enterococcus	Streptococcus A, B, C, G	Streptococcus pneumoniae	Haemophilus influenzae M. catarrhalis	N. gonorrhoeae	N. meningitidis	Anaerobes
CLSI	Cefotaxim	≤ 8/≥ 64	≤ 8/≥ 64	≤ 8/≥ 64	≤ 16/≥ 64	–	≤ 0.5/–	≤ 1/>4	≤ 2/–	≤ 0.5/–		–
EUCAST	Cefotaxim	≤ 1/≥ 2	–	–	*	–	≤ 0.5/> 0.5	≤ 0.5/> 2	≤ 0.12/> 0.12	≤ 0.12/> 0.12	≤ 0.12/> 0.12	–

^* The test results for staphylococci and methicillin (as well as oxacillin and cefoxitin) are applicable to all intravenously administered cephalosporins with the exception of ceftazidime, which should not be used to treat staphylococcal infections.

CLSI, Clinical Laboratory Standards Institute; EUCAST, European Committee on Antimicrobial Susceptibility.