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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):2948–2958. doi: 10.4049/jimmunol.0801692

FIGURE 6.

FIGURE 6

Reduced expression of NLRP12 during murine bone marrow differentiation is regulated by Blimp-1. (A) Murine bone marrow cells were isolated from C57BL/6 mice and differentiated in vitro with GM-CSF or stimulated with LPS for 3 hrs. Blimp-1 and NLRP12 expression were assessed by qPCR analysis of RNA isolated at the indicated time points. Data are a representative of three separate experiments. (B) Murine bone marrow cells were isolated from control ER+/+prdm1F/F mice or from ERCre/+prdm1F/F (48) mice in which Blimp-1 expression is knocked out under the control of the ER promoter . Bone marrow cells were differentiated in vitro with GM-CSF. NLRP12 expression was assessed by qPCR analysis of RNA isolated at the indicated time points. Data are an average of at least three separate experiments and error bars are calculated using SEM values.