Fig. 1.

The anatomy of the shoulder of a rat, where the rotator-cuff tendon inserts into the upper arm bone. (a) A cross-section of the supraspinatus tendon-to-bone insertion, as prepared for Raman spectroscopic analysis. (b) A magnified view of the tendon-to-bone insertion site, as seen in reflected light, was used to track the position of the Raman microprobe traverse (black circles) in individual tissue samples. At the insertion, a vertical dark stripe can be seen, which is frequently referred to as the “tidemark”.