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IL-7R+ pre-DP thymocytes develop in RAG2KO-Egr3-Tg mice in vivo. A, IL-7R expression on DN3 thymocytes. IL-7R expression on gated DN3 thymocytes from the various strains. Representative histogram of IL-7R expression on gated DN3 (Lin-CD25+CD44-) thymocytes is shown. B, RAG2KO-Egr3-Tg mice have increased IL-7R+ pre-DP thymocytes. Representative histogram of IL-7R expression on gated DN4/pre-DP (Lin-CD25-CD44-) thymocytes is shown.
