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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):57–64. doi: 10.1158/1055-9965.EPI-08-0377

Table 4. Two by two table analyses of PMS2 levels (in benign and cancer tissue), of total percent Gleason 4/5 and of both combined.

To determine the sensitivity (true positive) and specificity (true negative) of PMS2 alone and in combination with percent Gleason 4/5, a two-by-two table analyses was performed. The resulting percentages are shown above. PMS2 (B): PMS2 levels in benign tissue

Group Sensitivity Specificity
PMS2 in Cancer 61% 54%
PMS2 in Benign 72% 58%
% Gleason 4/5 76% 55%
% Gleason 4/5 + PMS2 (B) 88% 48%