Table 2.

Least-Squares Mean Change in the Intima–Media Thickness of the Common Carotid Artery and of the Combined Common and Internal Carotid Arteries from Year 1 to Year 6 of the Epidemiology of Diabetes Interventions and Complications Study, According to the Treatment Assignment in the Diabetes Control and Complications Trial.^*

Variable	Change in Intima–Media Thickness of Common Carotid Artery		Change in Combined Intima–Media Thickness
	Least-Squares Mean (95% CI)	P Value	Least-Squares Mean (95% CI)	P Value
	mm		mm
Conventional treatment	0.046 (0.023 to 0.068)		0.007 (−0.277 to 0.292)
Intensive treatment	0.032 (0.010 to 0.055)		−0.155 (−0.440 to 0.131)
Difference between treatment groups	0.013 (0.003 to 0.024)	0.01	0.162 (0.031 to 0.293)	0.02

^*The change in the intima–media thickness was used as the outcome to fit a general linear model, adjusted for sex, age, ultrasonography equipment used, and the year 1 thickness. CI denotes confidence interval.