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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Nov 20;29(2):246–253. doi: 10.1161/ATVBAHA.108.179218

Figure 1.

Figure 1

Figure 1

(A) Simvastatin reduced the formation of nodules in VIC cultures in a dose-dependent and ECM-dependent manner (fibrin - FB, laminin - LN, and tissue culture polystyrene - TCPS). * p < 0.01 vs. untreated control; ‘t/s’ refers to concurrent administration of 5 ng/mL TGF- β1 + 1 μmol/L simvastatin. (B) Simvastatin also reduced the contractile response of VICs cultured in collagen gels in a dose-dependent manner.