. Author manuscript; available in PMC: 2009 Jun 23.

Published in final edited form as: Cardiovasc Toxicol. 2008 Apr 30;8(2):57–69. doi: 10.1007/s12012-008-9015-1

Table 2.

Cardiac functional parameters by echocardiography

	I212N (N = 12)	I212 + HAART (N = 13)	H121N (N = 7)	H121N+HAART (N = 7)	Y955C (N = 13)	Y955C+HAART (N = 14)	WT (N = 38)	WT+HAART (N = 36)
LVEDD (mm)	3.52 ± 0.04	3.87 ± 0.07	3.31 ± 0.09	3.43 ± 0.15^ns	3.25 ± 0.08	3.80 ± 0.08	2.99 ± 0.05	3.15 ± 0.06
LVESD (mm)	1.67 ± 0.04	2.07 ± 0.05	1.57 ± 0.08	1.77 ± 0.12^ns	1.63 ± 0.09	2.15 ± 0.10	1.25 ± 0.04	1.43 ± 0.06
FS (%)	52.64 ± 0.83	46.44 ± 0.97	52.62 ± 1.64	48.37 ± 2.28^ns	50.01 ± 1.8	43.32 ± 1.6	58.05 ± 0.98	55.03 ± 1.08
HR (bpm)	336 ± 31	358 ± 8	342 ± 12	356 ± 18	312 ± 8	273 ± 17	383 ± 8	390 ± 12

WT cohorts were pooled from each 2 × 2 TG and normalized. Data presented are means +/- SEM for each functional parameter. Abbreviations include: left ventricular end diastolic dimension (LVEDD), left ventricular end systolic dimension (LVESD), fractional shortening (FS), and heart rate (HR). ns = no statistical difference between vehicle treated and AZT-treated