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Comparative analysis of the 8p23 inversion. FISH validation of 8p23 inversion in 27 HapMap individuals, eight chimpanzees, one bonobo, three gorillas, three orangutans and one macaque showed the inverted orientation (H2) as the most likely ancestral state. The inversion polymorphism might have occurred in the shared human and chimpanzee lineage and still be polymorphic in human and bonobo, but fixed in the chimpanzee population. Arrows indicate inverted chromosomes.
