Table 1.
Sequences of γ-MSH, [DPhe6]-γ-MSH, and [Pro5, DNaI(2′)8]-γ-MSH
Sequences of γ-MSH analogues | |
---|---|
γ-MSH | H-Tyr-Val-Nle-Gly-Pro-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 |
[DPhe6]-γ-MSH | H-Tyr-Val-Nle-Gly-Pro-DPhe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 |
[Pro5, DNaI(2′)8]-γ-MSH | H-Tyr-Val-Nle-Gly-Pro-Phe-Arg-DNaI(2′)-Asp-Arg-Phe-Gly-NH2 |
The bold letter s represent key residues for receptor binding and signaling