Table 1.
Previously characterized and new candidate TAS detected with the the first approach
| COG number | Toxin family | CV | COG number | Antitoxin family | CV |
| COG1848 | PIN | 1.1 | COG8614 | RHH | 1.0 |
| COG3832 | Aha1 family | 1.2 | COG0640 | ArsR family HTH | 0.8 |
| COG1708 | MNT | 0.9 | COG2250 | HEPN | 1.0 |
| COG4679 | RelE | 0.8 | COG5606 | HTH | 0.6 |
| COG2026 | RelE | 0.7 | COG7997 | MJ1172-like | 0.7 |
| COG3668 | RelE | 0.9 | COG2161 | StbD/axe | 0.5 |
| COG1708 | MNT | 0.4 | COG2445 | HEPN | 0.9 |
| COG3657 | RelE | 0.7 | COG3636 | HTH | 0.6 |
| COG1848 | PIN | 0.4 | COG2002 | AbrB/MazE/PemI | 0.9 |
| COG3668 | RelE | 0.9 | COG3609 | RHH | 0.4 |
| COG1669 | MNT | 0.7 | COG2361 | HEPN | 0.6 |
| COG9434 | MazF | 0.6 | COG5302 | CcdA | 0.7 |
| COG1598 | hicB | 0.7 | COG1724 | hicA | 0.6 |
| COG3549 | RelE | 0.7 | COG3093 | HTH | 0.6 |
| COG2026 | RelE | 0.4 | COG2161 | StbD_axe | 0.9 |
| COG3668 | RelE | 0.7 | COG9004 | RHH | 0.5 |
| COG6187 | RelE | 0.6 | COG2944 | HTH | 0.6 |
| COG1487 | PIN | 0.7 | COG4710 | RHH | 0.4 |
| COG1487 | PIN | 0.6 | COG4456 | AbrB/MazE/PemI | 0.4 |
| COG3742 | PIN | 0.5 | COG4423 | RHH | 0.4 |
| COG1487 | PIN | n/a | COG5450 | RHH | 0.5 |
COG numbers below 5600 correspond to the COGs that are available on the NCBI site: http://www.ncbi.nlm.nih.gov/COG/grace/uni.html
COGs that were predicted to include novel toxins and antitoxins in this work are shown by bold type.
CV – coefficient of variation.