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. Author manuscript; available in PMC: 2009 Nov 19.
Published in final edited form as: J Am Chem Soc. 2008 Oct 25;130(46):15702–15712. doi: 10.1021/ja8065557

Figure 2.

Figure 2

Leakage profile of calcein loaded SML liposomes. (A) Effect of chain length on osmotic stress-induced leakage. (B) Effect of linkage and formulation on osmotic stress-induced leakage. The fraction of calcein remaining in the liposome was calculated and plotted versus the osmotic gradient. The error of data is within 0.5%. (C) Contents leakage in 30% fetal bovine serum at 37 °C was monitored by measuring the fluorescence intensity change. The fraction of calcein remaining in the liposome was calculated and plotted versus the time of incubation. The control formulations have 40 mol % cholesterol.