Table 1.
Summary information on deletions with unequivocal effects on halothane sensitivity
| Strain Designation | Location of deletion (Chromosome arm:genomic coordinate) | Deletion size (bp) | Δ potency (95% CL) |
|---|---|---|---|
| +/ED4065 | 2R:20290189 | 540173 | −19.7% (−13.0 to −26.9) |
| +/ED5495 | 3R:5996223 | 716259 | −25.0% (−15.6 to −35.9) |
| +/ED2247 | 2R:7487611 | 388614 | −16.7% (−10.2 to −23.6) |
| +/ED2308 | 2R:8667875 | 216614 | −16.6% (−10.1 to −23.5) |
| +/ED1725 | 2R:3501429 | 542121 | +9.9% (+4.9 to +15.4) |
| +/ED1715 | 2R:3214456 | 589972 | +9.2% (+4.2 to +14.5) |
| +/ED1 | 2R:12914232 | 70595 | +16.1% (+10.6 to +22.5) |
| +/ED2751 | 2R:12744676 | 240132 | +15.6% (+10.1 to +21.8) |
The designated name indicates that the tested strains are heterozygotes between a strain without a deletion (+) and a strain (ED#) from the DrosDel collection carrying a deletion with the indicated number. The start point of each deletion is given with reference to the coordinate system of Drosophila Genome Release 5.1 (GenBank Accession AE013599.4 and AE014297.2). The change in potency of the deletion heterozygotes relative to the control heterozygote (+/parental ED line with no deletion) is deduced from eight-point concentration-response curves. These values, together with their 95% confidence limits, are calculated as described in Materials and Methods from the potency ratios derived from a logit analysis of the data.