TABLE 5.
Summary of other studies examining impact of LCIS on local control after breast-conserving therapy
% Local recurrence | ||||||||
---|---|---|---|---|---|---|---|---|
Author | Years (19xx - ) | Stage | Control # | LCIS # | Median follow-up (y) | LCIS + | LCIS − | p value |
Sasson et al.11 | 79–95 | I, II | 1208 | 65 | 6.3 | 29 | 6/10y | .0003 |
Moran et al.10 | prior 1992 | 0 – II | 1045 | 51 | 10.6 | 23 | 17/10y | NS |
Abner et al.7 | 68–86 | I – II | 1062 | 137 | 13.4 | 13 | 12/8y | NS |
Jolly et al.9 | 80–96 | I – II | 551 | 56 | 8.7 | 14 | 7/10y | .04 |
Ben-David et al.8 | 89–03 | 0 – II | 121 | 66 | 3.9 | 0 | 0.9/5y | NS |
Current study | 74–07 | 0 – II | 2607 | 290 | 5.2 | 6 | 6/10y | NS |
LCIS, lobular carcinoma in situ; NS, not significant