Table 1.

Selected clinical features of anti-p140–positive patients with juvenile DM compared with anti-p140–negative juvenile DM patients with myositis and anti-p155/140–positive juvenile DM patients^*

Characteristic	Anti-p140 positive (n = 37)†	Anti-p140 negative (n = 125)†	Anti-p155/140 positive (n = 28)
Age at disease onset, median (IQR) years	6 (2–10)	6 (4–9)	6 (4–10)
Age at diagnosis, median (IQR) years	7 (4.5–10.3)	7 (4–10)	7 (4–10)
Female sex	72	74	57
Type of skin lesion
Gottron's papules	85	82	100
Ulceration	34	23	57
Edema	35	35	64
Calcinosis	54‡	15	14
Lipoatrophy	18	13	18
Distribution of skin rash
Periorbital	79	69	96
Periungal	64	67	86
Small joints	67§	72	96
Large joints	52	51	75
Trunk	0¶	18	32

^*Except where indicated otherwise, values are the percent of patients. DM = dermatomyositis; IQR = interquartile range.

^†Not all patients had clinical data available for each feature.

^‡Corrected P (P_corr) < 0.005, odds ratio (OR) 7.0, 95% confidence interval (95% CI) 3.0–16.1 versus anti-p140–negative patients, and P_corr = 0.015, OR 7.1, 95% CI 2–25 versus anti-p155/140–positive patients.

^§P_corr = 0.05, OR 13.5, 95% CI 2–113 versus anti-p155/140–positive patients.

^¶P_corr = 0.02 versus anti-p140–negative patients, and P_corr < 0.005 versus anti-p155/140–positive patients.