Table 2. Prevalence of ECG abnormalities potentially relevant to prognosis in individuals without known CAD in different age groups.
Age 45-54 | Age 55-64 | Age 65-75 | P value | ||||
Men | Women | Men | Women | Men | Women | for age trend | |
(n = 693) | (n = 727) | (n = 836) | (n = 901) | (n = 559) | (n = 661) | Men/Women | |
Normal ECG | 65.1% | 69.1% | 53.2% | 61.3% | 36.7% | 47.4% | <0.0001 / <0.0001 |
Normal SR | 67.8% | 74.6% | 65.2% | 75.0% | 53.5% | 70.4% | <0.001 / 0.09 |
Atrial fibrillation/flutter | 0.4% | 0.4% | 1.9% | 0.2% | 4.5% | 2.3% | <0.0001 / <0.0001 |
Left axis deviation | 2.7% | 2.1% | 6.6% | 3.3% | 11.6% | 4.2% | <0.0001 / 0.07 |
AV block | 2.6% | 1.9% | 4.1% | 1.9% | 7.7% | 4.5% | <0.0001 / 0.002 |
BBB (complete) | 1.3% | 1.1% | 2.2% | 1.7% | 6.3% | 2.6% | <0.0001 / 0.1 |
BBB (incomplete) | 3.3% | 2.2% | 4.1% | 2.3% | 7.3% | 2.4% | <0.002 / 0.96 |
LVH | 2.2% | 0.8% | 4.0% | 1.6% | 5.4% | 2.1% | 0.01 / 0.1 |
Borderline LVH | 10.0% | 5.6% | 9.3% | 5.3% | 10.9% | 8.8% | 0.62 / 0.01 |
T-wave changes | 5.6% | 5.1% | 8.7% | 6.7% | 9.3% | 10.9% | 0.03 / <0.0001 |
Abnormal T axis | 1.6% | 1.0% | 2.2% | 1.0% | 2.5% | 2.1% | 0.51 / 0.1 |
QTc > 440 ms | 2.2% | 7.7% | 4.9% | 10.5% | 9.7% | 9.1% | <0.0001 / 0.14 |
Signs of ischemia | 5.9% | 6.7% | 10.4% | 10.5% | 13.0% | 15.4% | <0.0001 / 0.003 |
Signs of infarction | 4.6% | 4.3% | 7.5% | 5.0% | 13.3% | 8.3% | <0.001 / <0.001 |
Major ECG findings | 3.5% | 3.3% | 6.9% | 3.6% | 14.0% | 9.4% | <0.001 / <0.001 |
Data are based on the integrated 12SL-Code (GE Medical Systems, Freiburg), which is generated independently of individual investigators. In 110 persons without CAD, a digital ECG analysis was not available. Persons with CAD (n = 327) were excluded.
SR, sinus rhythm; AV, atrioventricular; BBB, bundle branch block; LVH, left ventricular hypertrophy. Major ECG findings: ST-segment depression, T-wave inversion, complete or incomplete AV block, frequent premature ventricular contractions or atrial fibrillation/flutter; further definitions in (19).