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. Author manuscript; available in PMC: 2009 Jun 25.
Published in final edited form as: Mech Dev. 2007 Jul 14;124(9-10):682–698. doi: 10.1016/j.mod.2007.07.003

Figure 6. Thecol locus encodes hdac1.

Figure 6

col maps close to the zebrafish hdac1 locus on LG 19 (A). A schematic showing the genomic organization of the zebrafish hdac1 gene (B). The zebrafish hdac1 gene has 15 exons and 14 introns spanning 9.94 kb of the genome and a T to G transversion in the intronic sequence adjacent to exon 5 causes aberrant splicing between exons 4 and 5 in col mutants (C). Aberrantly spliced hdac1 cDNA fragment in col with an additional 9 bp running in lane 1 can be distinguished from the wildtype product running in lane 2 (D). hdac1 expression is unaffected in 2 dpf col mutants (F, H) compared to wildtype (E, G).