Skip to main content
. Author manuscript; available in PMC: 2009 Jun 25.
Published in final edited form as: Mech Dev. 2007 Jul 14;124(9-10):682–698. doi: 10.1016/j.mod.2007.07.003

Figure 7. hdac1 morphants phenocopy col mutants and hdac1 RNA rescues col mutant phenotypes.

Figure 7

hdac1 MO injected wildtype embryos at 3 dpf (B) resemble uninjected col mutants (A). Reduced dlx2 expression (asterisk) and ectopically positioned facial hindbrain motor neurons (black arrowheads) in col mutants (D, G) are phenocopied in hdac1 morphants (E, H). The position of nV neurons in r2 are marked with arrows (G-I). hdac1 RNA is able to rescue axis extension and melanophore defects in col mutants (C). Telencephalon dlx2 expression and migration of facial hindbrain motorneurons is restored in col mutants injected with hdac1 RNA (F, I compared to D, G).