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. Author manuscript; available in PMC: 2009 Jun 25.
Published in final edited form as: Mech Dev. 2007 Jul 14;124(9-10):682–698. doi: 10.1016/j.mod.2007.07.003

Figure 9. Wildtype embryos treated late with TSA phenocopy col mutants.

Figure 9

Live wildtype embryos at 2dpf treated with 800 nM TSA late (at 16 hpf) resemble col mutants (A, compare to Fig. 7A). dlx2 expression is unaffected in these embryos (C) while the facial hindbrain motorneurons remain in r4 (arrowhead; E) as in col mutants. The position of nV neurons are shown with black arrows. Phenotypes observed at 2dpf in wildtype embryos treated with 50 nM TSA early (5 hpf) appear more severe (B). The forebrain dlx2 expression domain is reduced (D), similar to col mutants, and facial hindbrain motorneurons remain in r4 (F) in these embryos.