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. Author manuscript; available in PMC: 2009 Jun 25.
Published in final edited form as: J Sex Med. 2009 Mar;6(Suppl 3):311–319. doi: 10.1111/j.1743-6109.2008.01189.x

Figure 2. Relaxant responses due to NANC nerve stimulation and endothelium-dependent relaxation in cavernosal segments from control and TNF-α-infused mice.

Figure 2

(A) Representative traces showing NANC-induced relaxation in cavernosal segments from control (top) and TNF-α-infused (bottom) mice; (B) Frequency-responses curves elicited by EFS (NANC nerves stimulation) and (C) acetylcholine concentration-response curves in cavernosal strips pre-contracted with PE (10−5 M), from control (●) and TNF-α-infused (■) mice. Experimental values of the relaxations induced by EFS (n=9 and 10, respectively), and acetylcholine (n=7 and 10, respectively) were calculated relatively to the maximal changes from the contraction produced by PE in each tissue, which was taken as 100%. Data represent the mean ± SEM of n experiments. *, P<0.05 vs. control.