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New bone formation in rhBMP-7 incorporated PLLA nano-fibrous scaffolds retrieved 6 weeks after subcutaneous implantation in rats. (A) 5 μg rhBMP-7 adsorbed to scaffold; (B) 5 μg rhBMP-7 incorporated in nanosphere immobilized scaffold. H & E staining with original magnification of 100x. From Wei et al.[105] Copyright © 2007 by Elsevier. Reprinted with permission of Elsevier.
