Figure 3. E2 prevents cardiomyocyte apoptosis in Gq transgenic mice.
Cardiomyocyte apoptosis was assessed in hearts from placebo- or E2-treated FVB and Gq mice. Apoptotic cells were detected by TUNEL staining and counterstained with Hoechst 33258 to detect nuclei in the same fields. Arrowheads indicate apoptotic cells. Results are mean±SD values; n=10 mice in each group. *P<0.05 compared with placebo-treated FVB mice. †P<0.05 compared with placebo-treated Gq mice.
